The A2ML1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to A2ML1. This antibody recognizes Homo Sapiens, Human, and Rat antigen. The A2ML1 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq,ug 2015]