MyBioSource.com's Phospho-Chk2 (Thr68) Rabbit mAb is a Rabbit monoclonal antibody. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: Immunoprecipitation, and Western Blot.
Description
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function