The ATX3 Rabbit Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Ataxin 3, and ATXN3. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The ATX3 Rabbit Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
ataxin 3 (ATXN3) Homo sapiens Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016]