The TAF1C Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to TAF1C. This antibody recognizes Homo Sapiens, and Human antigen. The TAF1C Rabbit mAb Antibody has been shown to work in the following applications: Immunoprecipitation, and Western Blot.
Description
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3