MyBioSource.com's PHLP1 Rabbit Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot. The PHLP1 Rabbit Polyclonal Antibody was generated using PHLPP1 as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
PH domain and leucine rich repeat protein phosphatase 1 (PHLPP1) Homo sapiens This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]