The Phospho-Paxillin (Tyr118) Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to Paxillin, and Pxn. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Phospho-Paxillin (Tyr118) Rabbit mAb Antibody has been shown to work in the following applications: Western Blot.
Description
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions