MyBioSource.com's ING1 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The ING1 Polyclonal Antibody was generated using ING1 as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is nuclear protein that physically interacts with the tumor suppressor protein TP53 and is component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported