The Rabbit Anti-KRT2/Cytokeratin2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Homo Sapiens, and Human antigen. The Rabbit Anti-KRT2/Cytokeratin2 Antibody has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
KRT2 (Keratin 2) is a Protein Coding gene. The protein encoded by this gene is a member of the keratin gene family. The mRNA and protein expression of KRT2 was highly expressed in brown skin in comparison with that in white skin. After transfection with KRT2 in alpaca melanocytes, the relative mRNA and protein expression of KRT2, microphthalmia-associated transcription factor (MITF), tyrosinase (TYR), and tyrosinase-related protein 1 (TYRP1) in alpaca skin melanocytes were increased with significant differences; a further result was the increase of melanin production. KRT2 functions in alpaca hair color formation, which offered an essential theoretical basis for further exploration of the role of melanogenesis