MyBioSource.com's Recombinant RKIP Monoclonal Antibody is a Rabbit monoclonal antibody. The Recombinant RKIP Monoclonal Antibody was generated using PEBP1 as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Raf kinase inhibitor protein (RKIP),also termed phosphatidylethanolamine binding protein PEBP1,was initially identified as a potent inhibitor of Raf-1/MEK/ERK,NF-kB,and G-protein-coupled receptor signaling pathways. Later RKIP has been further identified as a metastasis suppressor and its loss of expression has been reported in various cancers. Its expression has been proposed as a prognostic marker for patients identified with the above cancers