The ZNF281 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ZNF281. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The ZNF281 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes