The Acetyl-Histone H2A (Lys9) Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to H2A clustered histone 4, H2A clustered histone 8, H2AC4, and H2AC8. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Acetyl-Histone H2A (Lys9) Rabbit mAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling