MyBioSource.com's Rabbit Anti-METTL21B Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
METTL21B (also known as EEF1AKMT3, FAM119B) is a member of the Family 16 group of methyltransferases. Despite its close relation to the other METTL21 proteins (METTL21A, C and D), METTL21B has a different substrate to both METTL21A (HSPA-KMT) and METTL21D (VCP-KMT). The main difference between these proteins is their N-terminal regions, beyond the core catalytic seven-beta-strand fold, which may therefore be responsible determining their substrate specificities. METTL21B is expressed at medium to high levels in every tissue type, and has been reported to localize to the nucleus, the cytoplasm and centrosomes. METTL21B has been implicated in multiple sclerosis because of changes in its expression in a susceptibility genotype