The CLK2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CDC Like Kinase 2, and CLK2. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The CLK2 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants