MyBioSource.com's CAPN3 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The CAPN3 Polyclonal Antibody was generated using Calpain 3, and CAPN3 as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
Calpain, a heterodimer consisting of a large and a small subunit, is major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed