MyBioSource.com's IKK gamma Rabbit mAb is a Rabbit monoclonal antibody. The IKK gamma Rabbit mAb Antibody was generated using IKBKG, and inhibitor of nuclear factor kappa B kinase regulatory subunit gamma as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot.
Description
The NF-kappaB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IkappaB proteins. Most agents that activate NF-kappaB do so through a common pathway based on phosphorylation-induced, proteasome-mediated degradation of IkappaB