The CFD Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CFD, and complement factor D. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The CFD Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease