Dnmt3a (C-12) Antibody sc-365769 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemDnmt3a (C-12) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-365769
Hostmouse
ClonalityMonoclonal
CloneC-12
Quantity200 µg/ml
NCBI Gene AliasesMmuIIIA, DNMT3A2, HESJAS, M.HsaIIIA, TBRS
Conjugate/TagUnconjugated
Antibody TypePrimary Antibodies
ApplicationsWB, IP, ELISA
Reactivitymouse, rat, human
NCBI Full Gene NameDNA methyltransferase 3 alpha, DNA methyltransferase 3A
TargetDnmt3a
FormatPurified
IsotypeIgG2b

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Multiple Epigenetic Mechanisms Functionally Cooperate to Silence Expression of Somatostatin Receptor Type 2 in Pancreatic Neuroendocrine TumorsbioRxivJanuary 16, 2026James P. Madigan, Stephen G. Andrews, Rivka B. Farrell, Steven D. Forsythe, Rupali Sharma, Michele Ceribelli, Craig J. Thomas, Kimia N. Shamsian, Shinjen Lin, Ken Chih-Chien Cheng, et al.utilized were: SSTR2 (BosterBio, M01689), DNMT1 (Epigentek, A-1700), DNMT3A (Santa Cruz Biotechnology, sc-365769), DNMT3B (Proteintech, 26971–1-AP), LSH/HELLS (Proteintech, 11955–1-AP) and HiBiT (Promega, N7200).

(2) Convergent DNA methylation abnormalities at enhancers and bivalent promoters in human growth disordersEpigenetics & ChromatinDecember 27, 2025Marie E. S. Wheeler, Yoshiko Takahashi, Jihye Lee, Camille T. Perez, Xiaoting Chen, Yuri Lee, Zachary S. Pope, Daniella J. Lu, Marcus Seldin, Ivan Marazzi, et al.incubated overnight at 4 °C with a primary antibody against DNMT3A (C-12, Santa Cruz Biotechnology, sc-365769), followed by HRP-conjugated anti-mouse IgG secondary antibody (Cell Signaling Technology, #7076) for

(3) Hyper-methylation and DNMT3A mediated LTC4S downregulation promoted lung adenocarcinoma tumorigenesis via mTORC1 signaling pathwayHeliyonJuly 15, 2024Yang Ren, Peng Zhang, Liqun Li, Mei Wang, Huiliang Hu, Yidan Shen, Ping Xu, Qingguo Wu, Feng LiPBS, collected and resuspended in lysis buffer. The DNA was fragmented by sonication, and Anti-DNMT3a (sc-365769, Santa Cruz, USA) or IgG antibodies were added into lysate to generate the protein/DNA complexes. Finally,

(4) Contribution of changes in the orexin system and energy sensors in the brain in depressive disorder - a study in an animal modelPharmacological reports : PRFebruary 1, 2024Głombik K, Kukla-Bartoszek M, Curzytek K, Basta-Kaim A, Budziszewska B.sc-271729), DNA methyltransferase 3a (Dnmt3a, Santa Cruz Biotechnology, Inc., Dallas, TX, USA, Cat. no.: sc-365769), DNA methyltransferase 3b (Dnmt3b, Santa Cruz Biotechnology, Inc., Dallas, TX, USA, Cat. no.: sc-376043),

(5) Epigenetic deregulation of MLF1 drives intrahepatic cholangiocarcinoma progression through EGFR/AKT and Wnt/β-catenin signalingHepatology communicationsAugust 1, 2023Tang Z, Yang Y, Chen W, Liang T.anti–DNA methyltransferase (DNMT)1 (1:500, Santa Cruz, sc-271729), anti-DNMT3A (1:1000, Santa Cruz, sc-365769), anti-DNMT3B (1:1000, Santa Cruz, sc-376043), anti-AKT (1:1000, CST, #4691), anti-phospho-AKT(Ser473,

(6) Epigallocatechin Gallate (EGCG), an Active Phenolic Compound of Green Tea, Inhibits Tumor Growth of Head and Neck Cancer Cells by Targeting DNA HypermethylationBiomedicinesMarch 5, 2023Agarwal A, Kansal V, Farooqi H, Prasad R, Singh VK.for p16 (#sc-1661), p21 (#sc-5246), p27 (#sc-1641), β-actin(#sc-47778), DNMT1 (#sc-271729), DNMT3a (#sc-365769), DNMT3b (#sc-376043), histone H3 (#sc-5661), 5-Aza-2-cytidine (5AzaDC; #sc-221003) from Santa Cruz Biotechnology

(7) "The Binomial ""Inflammation-Epigenetics"" in Breast Cancer Progression and Bone Metastasis: IL-1β Actions Are Influenced by TET Inhibitor in MCF-7 Cell Line"International journal of molecular sciencesDecember 6, 2022Bellavia D, Costa V, De Luca A, Cordaro A, Fini M, Giavaresi G, Caradonna F, Raimondi L.MA, USA), DNMT1 (1:1000, sc-271729, Santa Cruz Biotechnology, Inc., Dallas, TX, USA), DNMT3A (1:1000, sc-365769, Santa Cruz Biotechnology, Inc., Dallas, TX, USA), DNMT3B (1:1000, sc-376043, Santa Cruz Biotechnology, Inc

(8) DNA methylation-independent long-term epigenetic silencing with dCRISPR/Cas9 fusion proteinsLife science allianceJune 1, 2022Ding L, Schmitt LT, Brux M, Sürün D, Augsburg M, Lansing F, Mircetic J, Theis M, Buchholz F.nitrocellulose membrane (Millipore). The membranes were probed with primary antibodies against DNMT3A (sc-365769; Santa Cruz), DNMT3B (ab122932; Abcam), and Tubulin (sc-58880; Santa Cruz), and corresponding secondary

(9) FUNDC1 Induces Apoptosis and Autophagy Under Oxidative Stress via PI3K/Akt/mTOR Pathway in Cataract Lens CellsCurrent eye researchApril 1, 2022Dong D, Wu J, Sheng L, Gong X, Zhang Z, Yu C.

(10) Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progressionNature communicationsDecember 2, 2021Bolis M, Bossi D, Vallerga A, Ceserani V, Cavalli M, Impellizzieri D, Di Rito L, Zoni E, Mosole S, Elia AR, et al.antibodies used were: anti-GAPDH (sc-47724, Santa Cruz), anti-AR (sc-7305, Santa Cruz), anti-DNMT3A (sc-365769, Santa Cruz), anti-EZH2 (612667, BD Transduction Laboratory), anti-DNMT(5032S, Cell Signaling Technologies),

(11) Hydrogen sulfide prevents ethanol-induced ZO-1 CpG promoter hypermethylation-dependent vascular permeability via miR-218/DNMT3a axisJournal of cellular physiologyOctober 1, 2021Behera J, Kelly KE, Tyagi N.

(12) Hypermethylation of GNA14 and its tumor-suppressive role in hepatitis B virus-related hepatocellular carcinomaTheranosticsJanuary 1, 2021Song G, Zhu X, Xuan Z, Zhao L, Dong H, Chen J, Li Z, Song W, Jin C, Zhou M, et al.

(13) Phenethyl isothiocyanate reduces breast cancer stem cell-like properties by epigenetic reactivation of CDH1Oncology reportsJanuary 1, 2021Zhang T, Zhang W, Hao M.

(14) Does co-transplantation of mesenchymal and spermatogonial stem cells improve reproductive efficiency and safety in mice?Yearbook of Paediatric EndocrinologyOctober 23, 2020Kadam P, Ntemou E, Onofre J, Van Saen D, Goossens E1 h. After each step, the sections were washed in PBS for 5 min. The primary antibodies for DNMT3A (SC365769; Santa Cruz) and H4K5ac (Ab51997; Abcam, Cambridge, UK) were added at a dilution of 1:250 and 1: 1500,

(15) Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathwaysCell death and differentiationJune 1, 2020Dittmann J, Haydn T, Metzger P, Ward GA, Boerries M, Vogler M, Fulda S.

(16) Decitabine Augments Chemotherapy-Induced PD-L1 Upregulation for PD-L1 Blockade in Colorectal CancerCancersFebruary 17, 2020Huang KC, Chiang SF, Chen WT, Chen TW, Hu CH, Yang PC, Ke TW, Chao KSC.

(17) Protective Effects of Trimetazidine in Retarding Selenite-Induced Lens OpacificationCurrent eye researchDecember 1, 2019Fang W, Ye Q, Yao Y, Xiu Y, Gu F, Zhu Y.

(18) Does co-transplantation of mesenchymal and spermatogonial stem cells improve reproductive efficiency and safety in mice?Stem cell research & therapyOctober 22, 2019Kadam P, Ntemou E, Onofre J, Van Saen D, Goossens E.1 h. After each step, the sections were washed in PBS for 5 min. The primary antibodies for DNMT3A (SC365769; Santa Cruz) and H4K5ac (Ab51997; Abcam, Cambridge, UK) were added at a dilution of 1:250 and 1: 1500,

(19) Circulating Adipose Fatty Acid Binding Protein Is a New Link Underlying Obesity-Associated Breast/Mammary Tumor DevelopmentCell metabolismNovember 6, 2018Hao J, Zhang Y, Yan X, Yan F, Sun Y, Zeng J, Waigel S, Yin Y, Fraig MM, Egilmez NK, et al.

(20) Hypermethylated in cancer 1 (HIC1) mediates high glucose induced ROS accumulation in renal tubular epithelial cells by epigenetically repressing SIRT1 transcriptionBiochimica et biophysica acta. Gene regulatory mechanismsOctober 1, 2018Zeng S, Wu X, Chen X, Xu H, Zhang T, Xu Y.

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Dnmt3a (C-12) Antibody

Dnmt3a (C-12) Antibody from Santa Cruz Biotechnology, Inc.

Santa Cruz Biotechnology, Inc.

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Dnmt3a (C-12) Antibody from Santa Cruz Biotechnology, Inc.

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