Phospho-Met (Tyr1349) (130H2) Rabbit mAb 3133S from Cell Signaling Technology

Product Specs
ItemPhospho-Met (Tyr1349) (130H2) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number3133S
Quantity100 µl
ApplicationsW
ReactivityH, M, R
TargetMet (Tyr1349) phosphate
ModificationsMet (Tyr1349) phosphate
HostRabbit
NCBI Gene AliasesAUTS9, DA11, DFNB97, HGFR, RCCP2, c-Met
ClonalityMonoclonal
NCBI Full Gene NameMET proto-oncogene, receptor tyrosine kinase
Research AreaRTK
Clone130H2
Molecular Weight145

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) CXCR4, CXCR7 and PBRM1 are responsible for everolimus and cabozantinib resistance in human renal cancer cellsCell Death DiscoveryMarch 28, 2026Federica Auletta, Caterina Ieranò, Dario Guido Di Febbraro, Anna Maria Bello, Giuseppina Rea, Maria Napolitano, Francesca Galdiero, Giuseppe Guardascione, Anna Maria Trotta, Sara Santagata, et al.(T70) (Cat# 9455, RRID: AB_330949), 4EBP1 (53H11) (Cat# 9644, RRID: AB_2097841), pMET (Y1349) (Cat# 3133, RRID: AB_2181539), mouse monoclonal antibody for MET (L41G3) (Cat# 3148, RRID: AB_1031042), YY1 (D5D9Z)

(2) Host Protein Kinase C⍺: The novel Mitogen Activated Protein Kinase (MAPK) specific scaffold regulating nuclear export of influenza virus ribonucleoprotein complexesPLOS PathogensDecember 31, 2025Indrani Das Jana, Soumik Dey, Manoj Si, Arunava Roy, Arindam Mondalanti-NP (H16-L10-4R5,BEI Resources), anti-FLAG M2 (F1804-1MG,Sigma), anti-influenza A virus RNP (NR-3133, BEI Resources), MEK1/2 (L38C12, CST) and p44/42 MAPK (ERK1/2) (137F5, CST), PKCα (2056, CST), phospho-

(3) Autoregulation of the MET receptor tyrosine kinase by its intracellular juxtamembrane domainBiochem JDecember 17, 2025Edmond M. Linossi, Carla A. Espinoza, Gabriella O. Estevam, James S. Fraser, Natalia Jurafollowing phospho-specific antibodies were used to detect phosphorylation of MET Y1349 in the C-tail (#3133, CST) and Y1234/Y1235 in the activation loop (#3077, CST), using enhanced chemiluminescence (Amersham)

(4) Autoregulation of the MET receptor tyrosine kinase by its intracellular juxtamembrane domainBiochem JDecember 17, 2025Edmond M. Linossi, Carla A. Espinoza, Gabriella O. Estevam, James S. Fraser, Natalia Jurafollowing phospho-specific antibodies were used to detect phosphorylation of MET Y1349 in the C-tail (#3133, CST) and Y1234/Y1235 in the activation loop (#3077, CST), using enhanced chemiluminescence (Amersham)

(5) A Novel Role for the Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Delta Isoform in Hepatocellular ProliferationThe American Journal of PathologyFebruary 1, 2025Nicole J. Martucci, John Stoops, William Bowen, Anne Orr, Mary-Claire Cotner, George K. Michalopoulos, Bharat Bhushan, Wendy M. Mars,Cell Signaling Technologies,4685,WB,1:1000 p-Y1234/5 MET,Cell Signaling Technologies,3077,WB,1:1000 p-Y1349 MET,Cell Signaling Technologies,3133,WB,1:1000 Total MET,Cell Signaling Technologies,3127,WB,1:1000 p-Y1068 EGFR,Cell Signaling Technologies,3777,WB,1:1000 Total

(6) Deficiency of the HGF/Met pathway leads to thyroid dysgenesis by impeding late thyroid expansionNature communicationsApril 11, 2024Fang Y, Wan JP, Wang Z, Song SY, Zhang CX, Yang L, Zhang QY, Yan CY, Wu FY, Lu SY, et al.antibodies used for western blotting were anti-Met (#8198), anti-phospho-Met (#3077 for Tyr1234/1235, # 3133 for Tyr 1349), anti-Erk (#9102), anti-phospho-Erk (#9101), anti-Snail (#3879; Cell Signaling), and anti-Cdh1

(7) Three newly established immortalized mesothelial cell lines exhibit morphological phenotypes corresponding to malignant mesothelioma epithelioid, intermediate, and sarcomatoid types, respectivelyCancer cell internationalOctober 18, 2021Sato T, Nakanishi H, Akao K, Okuda M, Mukai S, Kiyono T, Sekido Y.Arbor, MI, USA). Antibodies Antibodies against NF2 (#12888), p16 (#92803), MET (#8198), phospho-MET (#3133), Oct-4A (#2840), Sox2 (#3579), Nanog (#4903), and KLF4 (#4038) were obtained from Cell Signaling Technologies

(8) Therapeutic Efficacy of ABN401, a Highly Potent and Selective MET Inhibitor, Based on Diagnostic Biomarker Test in MET-Addicted CancerCancersJune 15, 2020Kim J, Park KE, Jeong YS, Kim Y, Park H, Nam JH, Jung K, Son WS, Jung HS, Lee JH, et al.were as follows: anti-Met (#8198), anti-phospho-Met (Y1234/1235, #3077), anti-phospho-Met (Y1349, #3133), anti-Akt (#4691), anti-phospho-Akt (S473, #4060), anti-Erk1/2 (#4695), anti-phospho-Erk1/2 (T202/Y204,

(9) Increased RAB31 Expression in Cancer-Associated Fibroblasts Promotes Colon Cancer Progression Through HGF-MET SignalingFrontiers in oncologyJanuary 1, 2020Yang T, Zhiheng H, Zhanhuai W, Qian X, Yue L, Xiaoxu G, Jingsun W, Shu Z, Kefeng D.purchased from CST (Cell Signaling Technology, Danvers, MA, USA), including anti-HGF anti-phospho Met (#3133), anti-cMet (#8198), anti-Akt (#2920), anti-phospho-Akt (ser473, #4060), anti-pPDGFR (Tyr1009, #3124),

(10) The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistanceAutophagyJuly 1, 2019Huang X, Gan G, Wang X, Xu T, Xie W.(Cell Signaling Technology, 3077, for WB and immunohistochemistry [IHC]), anti-p-MET Y1349 (Cell Signaling Technology, 3133), anti-p-MET Y1356 (Abcam, ab73992), anti-p-MET Y1365 (Santa Cruz Biotechnology, sc-377548), anti-p-tyrosine

(11) Effect of NELL1 on lung cancer stem‑like cell differentiationOncology reportsMarch 1, 2019Zhai Y, Wei R, Sha S, Lin C, Wang H, Jiang X, Liu G.TX, USA), anti‑p‑MET (Tyr1349), (rabbit monoclonal antibody, anti‑human; dilution 1:1,000; cat. no. 3133; Cell Signaling Technology), c‑MET (rabbit monoclonal antibody, anti‑human; dilution 1:1,000; cat. no.

(12) Targeting c-met receptor tyrosine kinase by the DNA aptamer SL1 as a potential novel therapeutic option for myelomaJournal of cellular and molecular medicineDecember 1, 2018Zhang Y, Gao H, Zhou W, Sun S, Zeng Y, Zhang H, Liang L, Xiao X, Song J, Ye M, et al.from Selleck Chemicals (Houston, TX, USA). Antibodies against c‐met (#8198), phosphorylated c‐met (#3133), and GAPDH (#5174) were purchased from Cell Signaling Technology (Boston, MA, USA). Antibodies against

(13) Cross-talk between human airway epithelial cells and 3T3-J2 feeder cells involves partial activation of human MET by murine HGFPloS oneJanuary 1, 2018Hynds RE, Gowers KHC, Nigro E, Butler CR, Bonfanti P, Giangreco A, Prêle CM, Janes SM.

(14) Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cellsProceedings of the National Academy of Sciences of the United States of AmericaMarch 14, 2017Tavera-Mendoza LE, Westerling T, Libby E, Marusyk A, Cato L, Cassani R, Cameron LA, Ficarro SB, Marto JA, Klawitter J, et al.

(15) Synergistic Action of Genistein and Calcitriol in Immature Osteosarcoma MG-63 Cells by SGPL1 Up-RegulationPloS oneJanuary 1, 2017Engel N, Adamus A, Schauer N, Kühn J, Nebe B, Seitz G, Kraft K.

(16) LSD1 dual function in mediating epigenetic corruption of the vitamin D signaling in prostate cancerClinical epigeneticsJanuary 1, 2017Battaglia S, Karasik E, Gillard B, Williams J, Winchester T, Moser MT, Smiraglia DJ, Foster BA.

(17) Tyrosine kinase inhibitor SU11274 increased tumorigenicity and enriched for melanoma-initiating cells by bioenergetic modulationBMC CancerDecember 1, 2016Lucia Kucerova, Lucia Demkova, Svetlana Skolekova, Roman Bohovic, Miroslava Matuskovah. Specific phospho-Met antibody (Tyr1349, 130H2, rabbit mAb, Cell Signaling Technologies, cat. no. 3133) was used, monoclonal Anti-β-actin (SIGMA-ALDRICH, cat. no. A1978) served as a loading control. Immunoblots

(18) c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastomaThe Journal of clinical investigationMay 2, 2016Huang M, Liu T, Ma P, Mitteer RA Jr, Zhang Z, Kim HJ, Yeo E, Zhang D, Cai P, Li C, et al.Cell Signaling Technology, catalog 3077), and anti–PMet-Tyr1349 (1:100, Cell Signaling Technology, catalog 3133) antibodies overnight at 4°C. For mouse tissues, frozen sections were fixed with chilled acetone for

(19) Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cellsOncotargetSeptember 15, 2015Wang J, Ma L, Tang X, Zhang X, Qiao Y, Shi Y, Xu Y, Wang Z, Yu Y, Sun F.#2905), CD138 (Epitomics, #5608), MCAM (Epitomics, #2505), CD151 (Epitomics, #5901), CD166 (Epitomics, #3133), CD206 (Epitomics, #5307), RAGE (Abcam, #ab37647), Madcam1 (Epitomics, #5490), GFP (Epitomics, #1533),

(20) EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 functionProceedings of the National Academy of Sciences of the United States of AmericaJuly 21, 2015Phuchareon J, McCormick F, Eisele DW, Tetsu O.(3018, Cell Signaling Technology), phospho-Tyr1003, Tyr1234/1235, and Tyr1349 Met (3135, 3077, and 3133; Cell Signaling Technology), Met (3127, Cell Signaling Technology), phospho-Thy239/240 Shc (S434, Cell

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Phospho-Met (Tyr1349) (130H2) Rabbit mAb

Phospho-Met (Tyr1349) (130H2) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-Met (Tyr1349) (130H2) Rabbit mAb from Cell Signaling Technology

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