Phospho-Met (Tyr1234/1235) (3D7) Rabbit mAb 3129L from Cell Signaling Technology

Product Specs
ItemPhospho-Met (Tyr1234/1235) (3D7) Rabbit mAb
CompanyCell Signaling Technology
Price $936.00 Inquire
Catalog Number3129L
Quantity300 µl
ApplicationsW
ReactivityH, M, R
TargetMet (Tyr1234/Tyr1235) phosphate
ModificationsMet (Tyr1234/Tyr1235) phosphate
HostRabbit
NCBI Gene AliasesAUTS9, DA11, DFNB97, HGFR, RCCP2, c-Met
ClonalityMonoclonal
NCBI Full Gene NameMET proto-oncogene, receptor tyrosine kinase
Research AreaRTK
Clone3D7
Molecular Weight145 kDa

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Basal MET phosphorylation is an indicator of hepatocyte dysregulation in liver diseaseMolecular Systems BiologyJanuary 12, 2024Sebastian Burbano de Lara, Svenja Kemmer, Ina Biermayer, Svenja Feiler, Artyom Vlasov, Lorenza A D’Alessandro, Barbara Helm, Christina Mölders, Yannik Dieter, Ahmed Ghallab, et al.hepatocyte experiments,For primary human hepatocyte experiments pMET,Rabbit,1:2000,Cell Signaling,#3129 MET,Mouse,1:2000,Cell Signaling,#3148 pAKT,Rabbit,1:1000,Cell Signaling,#4058 AKT,Rabbit,1:2000,Cell

(2) Patient-derived exosomes facilitate therapeutic targeting of oncogenic MET in advanced gastric cancerScience AdvancesNovember 24, 2023Sujin Hyung, Jihoon Ko, You Jeong Heo, Steven M. Blum, Seung Tae Kim, Se Hoon Park, Joon Oh Park, Won Ki Kang, Ho Yeong Lim, Samuel J. Klempner, et al.Western blotting,β-Actin,1:1000,sc-4778,Santa Cruz Western blotting,MET,1:700,#8198,Cell Signaling Western blotting,pMET,1:500,#3129,Cell Signaling Western blotting,Vimentin,1:500,ab8978,Abcam Western blotting,N-cadherin,1:1000,sc-59987,Santa Cruz

(3) Preparation and Characterization of a Novel Cassava Starch-Based Phosphorus Releasing Super-Absorbent Polymer, and Optimization of the Performance of Water Absorption and Phosphorus ReleasePolymers (Basel)February 28, 2023Wenbo Bai, Bingyi Ji, Liren Fan, Qin Peng, Qi Liu, Jiqing Songgraft copolymerization with AA and AM. The spectral bands of PRP samples at approximately 3442 cm−1, 3129 cm−1, and 1632 cm−1 were the stretching vibration absorption peaks of adsorbed water, and the spectral

(4) Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigmsCancer cellNovember 8, 2021Hu H, Piotrowska Z, Hare PJ, Chen H, Mulvey HE, Mayfield A, Noeen S, Kattermann K, Greenberg M, Williams A, et al.(Thr202/Tyr204),Cell Signaling Technology,Cat# 9101 phospho-MET (Tyr1234/1235),Cell Signaling Technology,Cat# 3129 phospho-S6 (Ser240/244),Cell Signaling Technology,Cat# 5364 phospho-SMAD2 (Ser465/467),Cell Signaling Technology

(5) Effects of Iodonium Analogs on Nadph Oxidase 1 in Human Colon Cancer CellsAntioxidants (Basel)November 3, 2021Krishnendu K. Roy, Jiamo Lu, James H. Doroshowand phosphorylated proteins were purchased from Cell Signaling Technologies (Beverly, MA, USA); CS# 3129 for phosphorylated Met; CS# 3077 for total Met; CS# 56,554 for phosphorylated-Stat6; CS# 5397 for Stat6.

(6) Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and METJournal of Biological ChemistryApril 8, 2021Joost Neijssen et al.min and tested for MET phosphorylation using rabbit anti-phospho MET (Tyr1234–1235) (Cell Signaling 3129) and total MET protein using mouse anti-human MET antibody (Cell Signaling 3127). A score of 1 to 4

(7) TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase InhibitorsCancer DiscoveryJanuary 1, 2021Emiliano Cocco et al.Cell Signaling Technology), total ERK1/2 (9102S Cell Signaling Technology), Phospho-Met (Tyr1234/1235) (3129S, clone 3D7 Cell Signaling Technology), total MET (8198S, clone D1C2 Cell Signaling Technology), V5 (A00623–100

(8) Ex Vivo Drug Screening Informed Targeted Therapy for Metastatic Parotid Squamous Cell CarcinomaFrontiers in oncologyJanuary 1, 2021Nykänen N, Mäkelä R, Arjonen A, Härmä V, Lewandowski L, Snowden E, Blaesius R, Jantunen I, Kuopio T, Kononen J, et al.p-HER2 (Y1248) (R&D Systems Cat# AF1768), and p-cMET (Tyr1234/1235) (Cell Signaling Technology Cat# 3129). Secondary detection was performed with a goat anti-mouse IgG conjugated to DyLight 680 (Thermo Pierce

(9) Epithelial-to-mesenchymal transition is a resistance mechanism to sequential MET-TKI treatment of MET-amplified EGFR-TKI resistant non-small cell lung cancer cellsTranslational Lung Cancer ResearchNovember 19, 2020Michelle Simone Clement, Kristine Raaby Gammelgaard, Anders Lade Nielsen, Boe Sandahl Sorensen,Cell Signaling Technology,3127,Mouse,"145, 170",5% milk,"1:1,000",5% milk p-MET,Cell Signaling Technology,3129s,Rabbit,"145, 170",5% BSA,"1:1,000",5% BSA FGFR1,Cell Signaling Technology,9740S,Rabbit,"92, 120, 145",5%

(10) TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitorsCancer DiscovOctober 1, 2020Emiliano Cocco, Ji Eun Lee, Srinivasaraghavan Kannan, Alison M Schram, Helen H Won, Sophie Shifman, Amanda Kulick, Laura Baldino, Eneda Toska, Amaia Arruabarrena-Aristorena, et al.Cell Signaling Technology), total ERK1/2 (9102S Cell Signaling Technology), Phospho-Met (Tyr1234/1235) (3129S, clone 3D7 Cell Signaling Technology), total MET (8198S, clone D1C2 Cell Signaling Technology), V5 (A00623–100

(11) Cabozantinib, a Multityrosine Kinase Inhibitor of MET and VEGF Receptors Which Suppresses Mouse Laser-Induced Choroidal NeovascularizationJournal of ophthalmologyJanuary 1, 2020Zhang X, Zhu M, Xie L, Sun X, Xu J, Guo Y, Liu D, Shi Y, Xu X, Song E.study, including rabbit anti-HGF (ab83760, Abcam, Cambridge, MA, USA), rabbit anti-p-MET (Tyr1234/1235) (3129; Cell Signaling Technology, Beverly, MA, USA), mouse anti-MET (sc-8057; Santa Cruz Biotechnology, Santa

(12) De Novo Fatty Acid Synthesis-Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal CancerMolecular Cancer ResearchJanuary 1, 2019Naser Jafari et al.for western blot and immunofluorescent staining were purchased from Cell Signaling: FASN (#3180), pMET (#3129), MET (#3148), p-paxillin (#2541), paxillin (#2542), pFAK (#3283), FAK (#3285), pAkt (#4058L), Akt (#4691L),

(13) Vorinostat enhances gefitinib‑induced cell death through reactive oxygen species‑dependent cleavage of HSP90 and its clients in non‑small cell lung cancer with the EGFR mutationOncology reportsJanuary 1, 2019Park SE, Kim DE, Kim MJ, Lee JS, Rho JK, Jeong SY, Choi EK, Kim CS, Hwang JJ.HER2/ErbB2 (cat. no. 2242), pEGFR (Y1068) (cat. no. 2234), EGFR (cat. no. 2646), pMET (T1234/1235) (cat. no. 3129), MET (cat. no. 4560), pAKT (S473) (cat. no. 9271) and AKT (cat. no. 9272) were obtained from Cell Signaling Technology

(14) De Novo Fatty Acid Synthesis Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal CancerMol. Cancer Res.August 28, 2018Naser Jafari, James Drury, Andrew J. Morris, Fredrick O. Onono, Payton D. Stevens, Tianyan Gao, Jinpeng Liu, Chi Wang, Eun Y. Lee, Heidi L. Weiss, et al.for western blot and immunofluorescent staining were purchased from Cell Signaling: FASN (#3180), pMET (#3129), MET (#3148), p-paxillin (#2541), paxillin (#2542), pFAK (#3283), FAK (#3285), pAkt (#4058L), Akt (#4691L),

(15) The tumour suppressor OPCML promotes AXL inactivation by the phosphatase PTPRG in ovarian cancerEMBO reportsAugust 1, 2018Antony J, Zanini E, Kelly Z, Tan TZ, Karali E, Alomary M, Jung Y, Nixon K, Cunnea P, Fotopoulou C, et al.(#2165), phospho-EGFR Tyr1068 D7A5 XP rabbit mAb (#3777), phospho-Met Tyr1234/1235 3D7 rabbit mAb (#3129), and cMET 25H2 mouse mAb (#3127) were purchased from Cell Signaling Technology (CST). Phospho-ERK1 pT202/pY204+

(16) Oncogenic Function of a KIF5B-MET Fusion Variant in Non-Small Cell Lung CancerNeoplasia (New York, N.Y.)July 13, 2018Chien-Hung Gow, Yi-Nan Liu, Huei-Ying Li, Min-Shu Hsieh, Shih-Han Chang, Sheng-Ching Luo, Tzu-Hsiu Tsai, Pei-Lung Chen, Meng-Feng Tsai, Jin-Yuan ShihInc. (Danvers, MA) and were used for these analyses: anti-MET (#3148), anti-phospho-Y1234/Y1235-MET (#3129), anti-STAT3 (#4904), anti-phospho-Y705-STAT3 (#9138), anti-AKT (#9272), anti-phospho-S473-AKT (#4051),

(17) Upregulation of Bcl2 in NSCLC with acquired resistance to EGFR‑TKIOncology LettersNovember 9, 2017Hio Teng Cheong, Fei Xu, Chi Tung Choy, Connie Wun Chun Hui, Tony Shu Kam Mok, Chi Hang Wongcat. no. 2085; EGFR, cat. no. 2232; GAPDH, cat. no. 2118; Phospho‑MET (Tyr1234/1235) (3D7), cat. no. 3129 and pTEN (138G6), cat. no. 9559 (Cell Signaling Technology, Inc., Danvers, MA, USA); Bcl‑2, cat. no.

(18) Negative regulation of EGFR signalling by the human folliculin tumour suppressor proteinNature communicationsJune 28, 2017Laviolette LA, Mermoud J, Calvo IA, Olson N, Boukhali M, Steinlein OK, Roider E, Sattler EC, Huang D, Teh BT, et al.#4370 and 1:2,000; #9101), anti-pS6 (1:2,000; #5364), anti-HA (1:2,000; #3724), anti-pMET (1:1,000; #3129), total MET (1:1,000; #3148) and IgG control (#3900) antibodies were from Cell Signaling Technology

(19) The regulatory role of heparin on c-Met signaling in hepatocellular carcinoma cellsJournal of cell communication and signalingJune 1, 2017İşcan E, Güneş A, Korhan P, Yılmaz Y, Erdal E, Atabey N.(Israel). Heparin was from Applichem (A3004). Anti-EGR1 (15F7) cs 4351, anti-phosho-Met (Y-1234/1235) cs 3129, p21/Cip1/waf1 (DCS60) cs 2946 and anti-phosho- The regulatory role of heparin on c-Met 42/44 MAPK

(20) Regulation of intestinal myofibroblasts by KRas-mutated colorectal cancer cells through heparin-binding epidermal growth factor-like growth factorOncology ReportsMay 1, 2017Hideyoshi Kawasaki, Takuya Saotome, Tatsuya Usui, Takashi Ohama, Koichi SatoTokyo, Japan). The primary antibodies used were against these targets: c-Myc, GSK-3β phospho-Ser9, 3129 ERK p44/42 phospho-Thr202/Tyr204, Akt1 phospho-Ser473, p38 MAPK phospho-Thr180/Tyr182, p70 S6 Kinase

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Phospho-Met (Tyr1234/1235) (3D7) Rabbit mAb

Phospho-Met (Tyr1234/1235) (3D7) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-Met (Tyr1234/1235) (3D7) Rabbit mAb from Cell Signaling Technology

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