Synaptophysin Antibody PA1-1043 from Thermo Fisher Scientific

Product Specs
ItemSynaptophysin Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA1-1043
NCBI Gene AliasesSyp1, MRX96, Syn, p38, MRXSYP, XLID96, A230093K24Rik
ClonalityPolyclonal
Conjugate/TagUnconjugated
ReactivityBovine, Human, Mouse, Ovine, Rat
Quantity100 µg
FormatPBS with 1mg/mL BSA and 0.05% sodium azide
TargetSynaptophysin
HostRabbit
ApplicationsImmunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
NCBI Full Gene Namesynaptophysin
Concentration1 mg/mL
IsotypeIgG
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
Storage-20°C, Avoid Freeze/Thaw Cycles
Antibody TypePrimary
PurityAntigen affinity chromatography
ImmunogenSynthetic peptide corresponding to residues G(253) P G G Y G P Q D S Y G P Q G G Y Q P D(272) of rat Synaptophysin

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Thermo Fisher Scientific

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United States

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Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Optogenetic-induced α-synuclein accumulation reveals early synaptic dysfunction in experimental models of Parkinson's diseaseNPJ Parkinsons DisDecember 13, 2025Raquel Rodriguez-Aller, Beatriz Romero-Quineche, Marc Morissette, Razan Sheta, Thérèse Di Paolo, Armen Saghatelyan, Abid Oueslati(Burlington, MA, USA)",KO-validatedIlliano et al.105 Synaptophysin/rabbit,Synaptophysin Polyclonal/Cat#PA1-1043 (RRID: AB_2199026),amino acids 253-272,1:200,"Invitrogen (Waltham, MA, USA)","Vendor validated-Tissue-specific

(2) Neural synaptic vesicle autoimmunity following aerosolized porcine neural tissue exposure: insights into autoimmune inflammatory polyradiculoneuropathyEBioMedicineDecember 2, 2025Shannon R. Hinson, Pranjal Gupta, Naveen K. Paramasivan, P. James B. Dyck, Vanda A. Lennon, Daniel H. Lachance, Andrew M. Knight, Mohamed Rezk, Carley Karsten, Reghann G. LaFrance-Corey, et al.expression. Tissue immunofluorescence assay (TIFA) Patient serum and commercial synaptophysin-IgG (Invitrogen; #PA1-1043) or GAP43-IgG (Santa Cruz; #sc17790) were tested on cryosectioned adult mouse tissues: cerebellum, midbrain,

(3) Engineering Cortical Networks: An Open Platform for Controlled Human Circuit Formation and Synaptic Analysis In VitroAdvanced Healthcare MaterialsOctober 24, 2025Pacharaporn Suklai, Taylor Minckley, Cathleen Hagemann, Karolina Faber, Rosalind Norkett, Ludovica Guetta, Kelly O'Toole, Bethany Geary, Michael J. Devine, Andrea Seriocode,Dilution TBR1,Rabbit,Polyclonal,Abcam,Ab31940,1:300 CTIP2,Rat,IgG2a,Abcam,Ab18465,1:300 BRN2,Rabbit,Polyclonal,ThermoFisher,PA5‐30124,1:500 SATB2,Mouse,IgG1,Abcam,Ab51502,1:100 β3‐Tubulin,Mouse,IgG2b,Sigma,T5076,1:1000 MAP2,Mouse,IgG1,Sigma,13‐1500,1:750 OTX1/2,Rabbit,Polyclonal,Abcam,Ab21990,1:200 Nestin,Mouse,IgG1,Merck,MAB5326,1:200 PAX6,Mouse,IgG1,ThermoFisher,MA1‐109,1:200 GFAP,Chicken,Polyclonal,Abcam,Ab4674,1:2000 GFAP‐Cy3,Mouse,IgG1,Sigma,C9205,1:500 Synaptophysin,Rabbit,Polyclonal,ThermoFisher,PA1‐1043,1:500 PSD95,Mouse,IgG2a,ThermoFisher,MA1‐045,1:500 GFP,Rabbit,Polyclonal,Abcam,Ab6556,1:500 Primary

(4) The Beta Amyloid Core Hexapeptide Protects Against Full-Length Beta Amyloid-Induced Alteration of Dendritic Spine Morphology and DensityeNeuroAugust 25, 2025Ruth M. Shontell, David Araki, Kendra M. Ormsbee, Donovan D. Delgado, Robert A. NicholsThermo Fisher Scientific, #PA1-10005; 1:1,000) and, where studied, anti-synaptophysin (Thermo Fisher Scientific, #PA1-1043; 1:500) in 5% goat serum/0.1% TWEEN in 1× PBS for 18 h at 4°C. Cells were then washed three times with

(5) Neuromuscular dysfunction in patient-derived FUSR244RR–ALS iPSC model via axonal downregulation of neuromuscular junction proteinsNAR Molecular MedicineMarch 29, 2025Nicolai von Kügelgen, Katarzyna Ludwik, Samantha Mendonsa, Christine Römer, Erik Becher, Laura Breimann, Mara Strauch, Tommaso Mari, Sandrine Mongellaz, Binyamin Zuckerman, et al.Biolegend BLD-822601), α-synapsin (1:500, Merck AB1543), α-synaptophysin (1:250, Life Technologies PA11043), α-chat (1:100, Merck AB144P), α-β-actin (1:4.000, Sigma A2228), α-GAP43 (1:1000, Santa Cruz sc-10786),

(6) The Potential of Single-Transcription Factor Gene Expression by RT-qPCR for Subtyping Small Cell Lung CancerInternational journal of molecular sciencesFebruary 3, 2025Iñañez A, Del Rey-Vergara R, Quimis F, Rocha P, Galindo M, Menéndez S, Masfarré L, Sánchez I, Carpes M, Martínez C, et al.respectively. The sections were then incubated overnight at 4 °C with the primary antibody synaptophysin (SYP) (PA1-1043, Invitrogen, 1:100) and subsequently with the ImmPRESS Peroxidase (HRP) Polymer Reagent for signal amplification.

(7) Pharmacological inhibition of PLK2 kinase activity mitigates cognitive decline but aggravates APP pathology in a sex-dependent manner in APP/PS1 mouse model of Alzheimer's diseaseHeliyonOctober 30, 2024Martínez-Drudis L, Bérard M, Musiol D, Rivest S, Oueslati A.and 2),1:1000,,"UC Davis/NIH NeuroMab Facility (Davis, CA, USA)" Synapto-physin/rabbit,Synaptophysin/PA1-1043,253–272,1:25000,,"Invitrogen (Waltham, MA, USA)" Secondary antibodies,Secondary antibodies,Secondary

(8) Expression of the αVβ3 integrin affects prostate cancer sEV cargo and density and promotes sEV pro‐tumorigenic activity in vivo through a GPI‐anchored receptor, NgR2Journal of Extracellular VesiclesAugust 6, 2024Cecilia E. Verrillo, Fabio Quaglia, Christopher D. Shields, Stephen Lin, Andrew V. Kossenkov, Hsin‐Yao Tang, David Speicher, Nicole M. Naranjo, Anna Testa, William K. Kelly, et al.immunohistochemical analysis: rabbit polyclonal Abs against NgR2 (PA5‐98577, Invitrogen), Synaptophysin (PA1‐1043, Invitrogen) and non‐immune rabbit IgG (I5006, Sigma). 2.3 Immunoblotting analysis IB analysis was

(9) Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS miceeLifeApril 25, 2024Li A, Yi J, Li X, Dong L, Ostrow LW, Ma J, Zhou J.Primary antibodies used: neurofilament (DSHB 2H3 concentrate, 1:250), synaptophysin (Thermo Fisher PA11043, 1:400), Pax7 (SCBT sc-81648, 1:100), Cxcl12 (R&D MAB350, 1:200). Z-stack scans of glycerol-cleared

(10) Analysis of the interplay between MeCP2 and histone H1 during in vitro differentiation of human ReNCell neural progenitor cellsEpigeneticsDecember 1, 2023Siqueira E, Kim BH, Reser L, Chow R, Delaney K, Esteller M, Ross MM, Shabanowitz J, Hunt DF, Guil S, et al.ThermoFisher); rabbit Synapsin-1 1:1,000 (#5297, Cell Signalling Technologies); rabbit Synaptophysin 1:1,000 (PA1–1043, ThermoFisher); mouse Bassoon 1;1,000 (Ab82958, Abcam); HRP-conjugated Vinculin 1:2,000 (#18799, Cell Signalling

(11) Non-invasive systemic viral delivery of human alpha-synuclein mimics selective and progressive neuropathology of Parkinson’s disease in rodent brainsMolecular NeurodegenerationNovember 27, 2023Morgan Bérard, Laura Martínez-Drudis, Razan Sheta, Omar M. A. El-Agnaf, Abid Oueslatithe regulatory N-terminus,,1:1000,"Millipore (Temecula,CA, USA)" Synpato-physin/rabbit,Synaptophysin/PA1–1043,253–272 1:50000–,1:25000,,"Invitrogen (Waltham, MA, USA)" Secondary antibodies,Secondary antibodies,Secondary

(12) The Effect of Skeletal Muscle-Specific Creatine Treatment on ALS NMJ Integrity and FunctionInternational Journal of Molecular SciencesAugust 31, 2023Agnes Badu-Mensah, Xiufang Guo, Roxana Mendez, Hemant Parsaud, James J. Hickman(i.e., Myosin Heavy Chain (MyHC)) 1:30 (DSHB, A4_1025), Synaptophysin (syn) 1:1000 Fisher Scientific, PA1-1043), were added to the cultures and incubated overnight at 4 °C, after which they were rinsed thrice with

(13) An Integrated Systems Approach to Decode the Impact of Adolescent Nicotine Exposure in Utero and Postnatally Oxycodone Exposed OffspringResearch SquareApril 7, 2023Adrian Flores, Austin Gowen, Victoria L. Schaal, Sneh Koul, Jordan B. Hernandez, Sowmya V. Yelamanchili, Gurudutt Pendyala25,"1:2,000","1:5,000",Mouse,10 μg,Sigma Aldrich,S96S4 12,Synaptophysin,1:5.000,1:10.000,Rabbit,10 μg,Invitrogen,PA1-1043 13,ZO-1,"1:1,000","1:2,500",Rabbit,10 μg,Invitrogen,61-7300 Antibody inventory and details used in western blot

(14) Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibitionNeuronMarch 15, 2023Zhu Q, Mishra A, Park JS, Liu D, Le DT, Gonzalez SZ, Anderson-Crannage M, Park JM, Park GH, Tarbay L, et al.anti-Gephyrin,SCBT,"Cat# sc-25311, RRID:AB_627670" Rabbit polyclonal anti-Synaptophysin,Thermo Fisher Scientific,"Cat# PA1-1043, RRID:AB_2199026" Mouse monoclonal anti-PSD95,UC Davis/NIH NeuroMab,"Cat# 75-028, RRID:AB_2292909" Rabbit

(15) Spatially resolved transcriptomics reveals innervation-responsive functional clusters in skeletal muscleCell reportsDecember 20, 2022D'Ercole C, D'Angelo P, Ruggieri V, Proietti D, Virtanen L, Parisi C, Riera CS, Renzini A, Macone A, Marzullo M, et al.

(16) Muscle 4EBP1 activation modifies the structure and function of the neuromuscular junction in miceNature communicationsDecember 17, 2022Ang SJ, Crombie EM, Dong H, Tan KT, Hernando A, Yu D, Adamson S, Kim S, Withers DJ, Huang H, et al.

(17) The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancerScientific reportsNovember 7, 2022Quaglia F, Krishn SR, Sossey-Alaoui K, Rana PS, Pluskota E, Park PH, Shields CD, Lin S, McCue P, Kossenkov AV, et al.monoclonal Ab against the β3 integrin (13166S, Cell Signaling), rabbit polyclonal Abs against SYP (PA1-1043, Invitrogen), and NgR2 (PA5-98577, Invitrogen) were also used. Rabbit IgG (I5006, Sigma) was used as

(18) ENT-A010, a Novel Steroid Derivative, Displays Neuroprotective Functions and Modulates Microglial ResponsesBiomoleculesMarch 9, 2022Yilmaz C, Rogdakis T, Latorrata A, Thanou E, Karadima E, Papadimitriou E, Siapi E, Li KW, Katsila T, Calogeropoulou T, et al.vehicle (DMSO). Cells were then fixed with 4% PFA and immunostained against TUJ1, Synaptophysin (1:1000, PA1-1043, Invitrogen, MA, USA) and anti-mouse Alexa fluor 488 (1:1000, A-11029, Invitrogen, MA, USA) or anti-rabbit

(19) Development and Biological Characterization of a Novel Selective TrkA Agonist with Neuroprotective Properties against Amyloid ToxicityBiomedicinesMarch 6, 2022Rogdakis T, Charou D, Latorrata A, Papadimitriou E, Tsengenes A, Athanasiou C, Papadopoulou M, Chalikiopoulou C, Katsila T, Ramos I, et al.for 4 h. Cells were then fixed with 4% PFA and immunostained against Tuj1 and Synaptophysin (1:1000, PA1-1043, Invitrogen, Waltham, MA, USA), anti-mouse Alexa fluor 488 (1:1000, A-11029, Invitrogen, Waltham, MA,

(20) Whole-mount Staining of Mouse Diaphragm Neuromuscular JunctionsBio-protocolNovember 5, 2021Sha R, Wang Z, You X, Liu Y, Xie Z, Feng Y.

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Synaptophysin Antibody

Synaptophysin Antibody from Thermo Fisher Scientific

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Synaptophysin Antibody from Thermo Fisher Scientific

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