Phospho-PDGF Receptor beta (Tyr1021) (6F10) Rabbit mAb 2227S from Cell Signaling Technology

Product Specs
ItemPhospho-PDGF Receptor beta (Tyr1021) (6F10) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number2227S
Quantity100 µl
ApplicationsW
ReactivityH, M, R
TargetPDGFR-b (Tyr1021) phosphate
ModificationsPDGFR-b (Tyr1021) phosphate
HostRabbit
NCBI Gene AliasesCD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT
ClonalityMonoclonal
NCBI Full Gene Nameplatelet derived growth factor receptor beta
Research AreaRTK
IsotypeIgG
Clone6F10
Molecular Weight190

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Targeting ABCD1-ACOX1-MET/IGF1R axis suppresses multiple myelomaLeukemiaMarch 1, 2025Zhannan Han, Zhibo Yan, Zhehan Ma, Yihui Wang, Maja Beus, Junqi Lu, Loren B. Weidenhammer, Kiran Lakhani, Jingyun Lee, John D. Civils, et al.Antibodies for MET (1:1000; 8198T), ERBB2 (1:1000; 2165T), PDGFRB (1:300; 3169T), p-PDGFRbY1021 (1:300; 2227T), PDGFRbY740 (1:300; 3168T), AKT (1:1000; 9272), p-AKTS473 (1:1000; 4060T), ERK (1:1000; 9102S), and

(2) Meis1 Targets Protein Tyrosine Phosphatase Receptor J in Fibroblast to Retard Chronic Kidney Disease ProgressionAdvanced ScienceOctober 1, 2024Mi Bai, Shuang Xu, Mingzhu Jiang, Yuxian Guo, Dandan Hu, Jia He, Ting Wang, Yu Zhang, Yan Guo, Yue Zhang, et al.Bioss (Beijing, China). Antibody against CyclinD1 (Cat No. 2978S), Anti‐p‐PDGFRβ (Tyr1021) (Cat No. 2227S), SimpleChIP Enzymatic Chromatin IP Kit (Magnetic Beads, Cat No. 9003S), and SimpleChIP Universal qPCR Master Mix

(3) PDGFD switches on stem cell endothelial commitmentAngiogenesisNovember 1, 2022Lu W, Xu P, Deng B, Zhang J, Zhan Y, Lin X, Xu X, Xia Z, Yang X, Zeng X, et al.Cell Signaling Technology), anti-PDGFR-β (3169, Cell Signaling Technology), anti-Phospho PDGFR-β (Tyr1021) (2227, Cell Signaling Technology), anti-PECAM1 (222783, Abcom), anti-Phospho STAT3 (9145, Cell Signaling Technology),

(4) Syndecan-1 Promotes Angiogenesis in Triple-Negative Breast Cancer through the Prognostically Relevant Tissue Factor Pathway and Additional Angiogenic RoutesCancersMay 12, 2021Nassar E, Hassan N, El-Ghonaimy EA, Hassan H, Abdullah MS, Rottke TV, Kiesel L, Greve B, Ibrahim SA, Götte M.functions in breast cancer cell adhesion, migration, and resistance to irradiation. FEBS J. 2013, 280, 2216–2227. [CrossRef] Szatmári, T.; Ötvös, R.; Hjerpe, A.; Dobra, K. Syndecan-1 in Cancer: Implications for Cell Signaling

(5) Shining light on dark matter in the genomeProceedings of the National Academy of SciencesDecember 10, 2019Dongyin Guan, Mitchell A. LazarCarroll, Pioneer transcription factors: Establishing competence for gene expression. Genes Dev. 25, 2227–2241 (2011). 7 S. Heinz, C. E. Romanoski, C. Benner, C. K. Glass, The selection and function of cell

(6) An Exploratory Factor Analysis of Sensor-Based Physical Capability AssessmentSensors (Basel)May 14, 2019Alice Coni, Sabato Mellone, Marco Colpo, Jack M. Guralnik, Kushang V. Patel, Stefania Bandinelli, Lorenzo Chiariwalk (gait speed, "Walking Impairment”, 7MW1, "Gait Irregularity”, 7MW2) and, Sensors 2019, 19, 2227 19 of 24 as expected, performed better in the CST test ("Sit-to-Stand Jerkiness”, CST2, "ML Dynamic

(7) NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathyNature communicationsAugust 27, 2018Dubrac A, Künzel SE, Künzel SH, Li J, Chandran RR, Martin K, Greif DM, Adams RH, Eichmann A.#4549, Cell Signaling), anti-PDGFRβ 1009 (1/1000, #3124, Cell Signaling), anti-PDGFRβ 1021 (1/1000, #2227, Cell Signaling), anti-PDGFRβ (1/1000, #3169, Cell Signaling), anti-p44/42 MAP kinase (1/1000, phospho-ERK,

(8) Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancerNature MedicineApril 1, 2018Amritha Nair et al.9355) phospho-P70 S6 Kinase (T421/S424) (Cell Signaling 9204); phospho-PDGFRβ (Y1021, Cell Signaling 2227); PDGFRB (Cell Signaling 3169); phospho-Met (Y1234/35 Cell Signaling 3077); MET (Cell Signaling 8198),

(9) RUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYCLeukemiaOctober 1, 2017V Selvarajan et al.(Cell Signaling Technology, Danvers, MA, USA) according to the manufacturer’s instructions. Leukemia (2017) 2219 – 2227 Luciferase reporter assay The RUNX3 enhancer sequence (Supplementary Methods) that contains essential

(10) Fibrinolytic crosstalk with endothelial cells expands murine mesenchymal stromal cellsBloodAugust 25, 2016Dhahri D, Sato-Kusubata K, Ohki-Koizumi M, Nishida C, Tashiro Y, Munakata S, Shimazu H, Salama Y, Eiamboonsert S, Nakauchi H, et al.(Cell Signaling; 2148), p-PDGFRa/Tyr 720 (Santa Cruz Biotech; sc-12910), or PDGFRb-PY1021 (Cell Signaling; 2227). Membranes were stained with secondary antibody conjugated with horseradish peroxidase (HRP; Nichirei; rabbit-HRP

(11) Inducible and coupled expression of the polyomavirus middle T antigen and Cre recombinase in transgenic mice: an in vivo model for synthetic viability in mammary tumour progressionBreast Cancer ResearchFebruary 1, 2014Trisha Rao, Jill J Ranger, Harvey W Smith, Sonya H Lam, Lewis Chodosh, William J MullerDilworth, Ab750, 1:1000), c-Myc (Santa Cruz Biotechnology #764); P-PDGFRβ (Y1021) (Cell Signaling #2227, 1:1,000); PDGFRβ (Cell Signaling #3175, 1:1,000); α-tubulin (Cell Signaling #2125). Horse radish peroxidase

(12) Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPDDisease models & mechanismsNovember 1, 2013Heidler J, Fysikopoulos A, Wempe F, Seimetz M, Bangsow T, Tomasovic A, Veit F, Scheibe S, Pichl A, Weisel F, et al.CC3 (#9661, Cell Signaling Technology), PDGFRβ (#4564, Cell Signaling Technology), pPDGFRβ-Y1021 (#2227, Cell Signaling Technology), KGF (AF-251-NA, R&D Systems), elastin (#PR385, Elastin Products Company),

(13) Tissue transglutaminase promotes PDGF/PDGFR-mediated signaling and responses in vascular smooth muscle cellsJournal of cellular physiologyMay 1, 2012Zemskov EA, Mikhailenko I, Smith EP, Belkin AM.Cell Signaling Technology (PDGFRα, 3164; pTyr740-PDGFRβ, 3168; pTyr771-PDGFRβ, 3124; pTyr1021-PDGFRβ, 2227; pThr202-pTyr204-ERK1/2, 9101; pTyr418-src, 2113; pThr308-Akt1, 4056; pSer473-Akt1, 2337; pTyr542-Shp-2,

(14) "Smart fats", healthy brain and function of lipid-sensing NMDA receptorsAdvances in Biological ChemistryJanuary 1, 2012Anna Kloda, Boris MartinacJohnson, T.D. (1996) Modulation of channel function by polyamines. Trends in Pharmacological Sciences, 17, 2227. doi:10.1016/0165-6147(96)81566-5 [84] Williams, K. (1997) Modulation and block of ion channels: A new

(15) The Stent-Eluting Drugs Sirolimus and Paclitaxel Suppress Healing of the Endothelium by Induction of AutophagyThe American Journal of PathologyNovember 1, 2009Shin-ichiro Hayashi, Akitsugu Yamamoto, Fukka You, Kentaro Yamashita, Yuka Ikegame, Masahiro Tawada, Tamotsu Yoshimori, Shigeomi Shimizu, Shigeru NakashimaYanagido, Gifu City, Gifu 501-1194, Japan. E-mail: Shin559182@aol.com. Sirolimus and Endothelial Autophagy 2227 AJP November 2009, Vol. 175, No. 5 Materials and Methods cording to protocols approved by the Animal

(16) Focal adhesion kinase is required for neural crest cell morphogenesis during mouse cardiovascular developmentThe Journal of clinical investigationAugust 1, 2009Vallejo-Illarramendi A, Zang K, Reichardt LF.Erk2 The Journal of Clinical Investigation http://www.jci.org Volume 119 Number 8 August 2009 2227 research article mAb (catalog no. 05-157), and GAPDH mAb (catalog no. MAB374) (Millipore). Filamentous

(17) The Mesoscale Structure of a Nocturnal Dryline and of a Frontalâ€“Dryline MergerMonthly Weather ReviewNovember 1, 2000David B. Parsons, Melvyn A. Shapiro, Erik Millerapproximately NW–SE (1378– 3178 in meteorological coordinates with 908–1808 as east–west). (b) An RHI taken at 2227 CST 13 May 1985. The horizontal component of the measured radial velocity is indicated with the arrows.

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Phospho-PDGF Receptor beta (Tyr1021) (6F10) Rabbit mAb

Phospho-PDGF Receptor beta (Tyr1021) (6F10) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-PDGF Receptor beta (Tyr1021) (6F10) Rabbit mAb from Cell Signaling Technology

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