ROCK2 Antibody 8236S from Cell Signaling Technology

Product Specs
ItemROCK2 Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number8236S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R
TargetROCK2
Molecular Weight160
HostRabbit
NCBI Gene AliasesROCK-II
NCBI Full Gene NameRho associated coiled-coil containing protein kinase 2
ClonalityPolyclonal
Research AreaCytoskeletal Signaling

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Website: Technical Support

(1) Shroom3-Rock interaction and profibrotic function: Resolving mechanism of an intronic CKD risk allelebioRxivJanuary 16, 2026Anand Reghuvaran, Ashwani Kumar, Qisheng Lin, Nallakandi Rajeevan, Zeguo Sun, Hongmei Shi, Gabriel Barsotti, E M Tanvir, John Pell, Sudhir Perincheri, et al.were: anti-MYPT(Cell Signaling), anti-phosphoMYPT-T696(), anti-ROCK1(Cell Signaling), anti-ROCK2 (#8236, Cell Signaling), anti-HSP-90 (#4877, Cell Signaling), anti-SHROOM3 (#SAB3500818, Millipore-Sigma; #LS-C679459,

(2) A Novel Role of Hyaluronan and Its Membrane Receptors, CD44 and RHAMM, in Obesity-Related Kidney PathologyBiomoleculesNovember 14, 2025Bingxue Qi, Vishal Musale, Xiong Weng, Ayman K. Banah, Alexander Lawlor, Colin E. Murdoch, Abigail C. Lay, Kate J. Heesom, Richard J. M. Coward, Christopher L. O’Connor, et al.Danvers, MA, USA: #E7k2y, #E7S4Y, #8828S, #3102S, #9211, #9212, #9251, #9252, #4060, #9272, #4370, #4695, #8236, respectively), and TGF-β1 (#ab179695, Abcam, Cambridge, UK). GAPDH (#5174, Cell Signaling, Danvers,

(3) ZXDC enhances cervical cancer metastasis through IGF2BP3-mediated activation of RhoA/ROCK signalingiScienceAugust 18, 2023Mao Y, Jiang X, Guo P, Ouyang Y, Chen X, Xia M, Wu L, Tang Z, Liang T, Li Y, et al.1:1000), anti-ROCK1 (Cell Signaling Technology, #4035, 1:1000), anti-ROCK2 (Cell Signaling Technology, #8236, 1:1000), anti-IGF2BP3 (Proteintech, 14642-1-AP, 1:2000), anti-p-CofilinS3 (Cell Signaling Technology,

(4) Apelin prevents diabetes-induced poor collateral vessel formation and blood flow reperfusion in ischemic limbFrontiers in Cardiovascular MedicineAugust 11, 2023Stéphanie Robillard, Kien Trân, Marie-Sophie Lachance, Tristan Brazeau, Elizabeth Boisvert, Farah Lizotte, Mannix Auger-Messier, Pierre-Luc Boudreault, Éric Marsault, Pedro GeraldesA (RhoA) (2117S), rho-associated coiled-coil-containing protein kinase (ROCK) 1 (4035S) and ROCK-2 (8236S), and secondary antibody of anti-rabbit (7,074 V) and anti-mouse (7076S) peroxidase-conjugated from

(5) The SARS-CoV-2 spike S1 protein induces global proteomic changes in ATII-like rat L2 cells that are attenuated by hyaluronanAmerican Journal of Physiology-Lung Cellular and Molecular PhysiologyApril 1, 2023James A. Mobley, Adam Molyvdas, Kyoko Kojima, Israr Ahmad, Tamas Jilling, Jian-Liang Li, Stavros Garantziotis, Sadis Matalondilution; Cat. No. 3742S; Cell Signaling Technology, Beverly, MA) and ROCK2 (1:1,000 dilution; Cat. No. 8236; Cell Signaling Technology, Beverly, MA) or pTyr722-ROCK2 antibody (Cat. No. SAB4301564; MilliporeSigma).

(6) Dissecting protein tyrosine phosphatase signaling by engineered chemogenetic control of its activityThe Journal of cell biologyAugust 1, 2022Fauser J, Huyot V, Matsche J, Szynal BN, Alexeev Y, Kota P, Karginov AV.rabbit), anti-phospho-Gab1 (Tyr659; cat. no. 12745; Cell Signaling, rabbit), anti-ROCK II (cat. no. 8236; Cell Signaling, rabbit), anti-phospho-ROCK II (Tyr722; cat. no. SAB4301564; Sigma-Aldrich, rabbit),

(7) Hexokinase 2-driven glycolysis in pericytes activates their contractility leading to tumor blood vessel abnormalitiesNature communicationsOctober 14, 2021Meng YM, Jiang X, Zhao X, Meng Q, Wu S, Chen Y, Kong X, Qiu X, Su L, Huang C, et al.(Sagecreation). Rabbit mAb against human ROCK1 (CST, 4035, 1:1000) and rabbit mAb against human/mouse ROCK2 (CST, 8236S, 1:1000) were used in this part. Hsc70 was used as loading control (Santa Cruz, sc-7298, 1:1000). Primary

(8) miR-208b Reduces the Expression of Kcnj5 in a Cardiomyocyte Cell LineBiomedicinesJune 23, 2021Julia Hupfeld et al.incubated with primary antibodies (from Cell Signaling Technology, Danvers, MA, USA: ROCK2: 1:1000, 8236, Ran: 1:1000, 4462, β-actin (13E5): 1:1000, 4970, HSP90: 1:1000, 4874) at 4 ◦ C overnight. The bound

(9) Protective effects of curcumin against rat intestinal inflammation‑related motility disordersMolecular medicine reportsMay 1, 2021Yao Y, Luo R, Xiong S, Zhang C, Zhang Y.Cell Signaling Technology, Inc.), Rho A (cat. no. 27213‑1‑AP; ProteinTech Group, Inc.), ROCKII (cat. no. 8236s; Cell Signaling Technology, Inc.), MLC20 (cat. no. 3672s; Cell Signaling Technology, Inc.), p‑MLC20 (cat.

(10) Tetrahydroxystilbene glucoside protects against LPS-induced endothelial dysfunction via inhibiting RhoA/ROCK signaling and F-actin remodelingGeneral physiology and biophysicsMarch 16, 2020Yan Qi, Xiuying Liang, Xia Hu, Haiyan He, Lian Tang, Wenjuan Yao(#2117), MYPT1 (#2634), phospho-MYPT1 (Thr696 and Thr853) (#5163 and #4563), ROCK1 (#4035), ROCK2 (#8236), GAPDH (#2118), and von Willebrand factor (#65707) were obtained from Cell Signaling Technology Qi

(11) Xanthoceraside prevented synaptic loss and reversed learning-memory deficits in APP/PS1 transgenic miceThe journal of physiological sciences : JPSMay 1, 2019Jin G, Zhu L, Liu P, Xu Q, Qi Y, Zhou X, Xu J, Ji X, Chi T, Zou L.USA), rabbit anti-RhoA (1:1000, Cell Signaling, 2117, USA), rabbit anti-ROCK2 (1:800, Cell Signaling, 8236, USA), mouse anti-Snk (1:300, Santa Cruz, sc-374643, USA), goat antiSPAR (1:300, Santa Cruz, sc-31615,

(12) A viral Sm-class RNA base-pairs with mRNAs and recruits microRNAs to inhibit apoptosisNatureOctober 12, 2017Gorbea C, Mosbruger T, Cazalla D.Life Span Biosciences and Proteintech Group, respectively. Antibodies to DDX5 (Catalog # 4387S), Rock2 (Catalog # 8236S), Rac1/2/3 (Catalog # 2465S), N-Wasp (Catalog # 4848S), Fas (Catalog # 8023S) and retinoblastoma (Catalog

(13) Telomere DNA damage signaling regulates cancer stem cell evolution, epithelial mesenchymal transition, and metastasisOncotargetOctober 6, 2017Lagunas AM, Wu J, Crowe DL.

(14) Adipocyte-Specific Mineralocorticoid Receptor Overexpression in Mice Is Associated With Metabolic Syndrome and Vascular Dysfunction: Role of Redox-Sensitive PKG-1 and Rho KinaseDiabetesAugust 1, 2016Nguyen Dinh Cat A, Antunes TT, Callera GE, Sanchez A, Tsiropoulou S, Dulak-Lis MG, Anagnostopoulou A, He Y, Montezano AC, Jaisser F, et al.#9571, Cell Signaling Technology), anti-eNOS (1:1000, #9572), anti-ROCK isoform 2 (ROCK2; 1:1000; #8236, Cell Signaling Technology), anti-RhoA (26C4) (1:500; #sc-418, Santa Cruz Biotechnology), and anti–PKG-1

(15) Vascular O-GlcNAcylation augments reactivity to constrictor stimuli by prolonging phosphorylated levels of the myosin light chainBrazilian Journal of Medical and Biological ResearchAugust 15, 2014V.V. Lima, N.S. Lobato, F.P. Filgueira, R.C. Webb, R.C. Tostes, F.R. Giachinianti-protein kinase CPI-17 (#32213, 1:1000; Abcam, USA), anti-MYPT-1 (#2634), anti-rho-kinase (ROCK)-α (#8236), anti-ROCK-β (#4035), anti-MLC (#8505) and anti-RhoA (#2117) (all 1:1000; Cell Signaling, USA, or BD

(16) Vascular O-GlcNAcylation augments reactivity to constrictor stimuli by prolonging phosphorylated levels of the myosin light chainBraz. J. Med. Biol. ResAugust 15, 2014V.V. Lima, N.S. Lobato, F.P. Filgueira, R.C. Webb, R.C. Tostes, F.R. Giachinianti-protein kinase CPI-17 (#32213, 1:1000; Abcam, USA), anti-MYPT-1 (#2634), anti-rho-kinase (ROCK)-α (#8236), anti-ROCK-β (#4035), anti-MLC (#8505) and anti-RhoA (#2117) (all 1:1000; Cell Signaling, USA, or BD

(17) Mimicry and antibody-mediated cell signaling in autoimmune myocarditisJournal of immunology (Baltimore, Md. : 1950)December 1, 2006Li Y, Heuser JS, Cunningham LC, Kosanke SD, Cunningham MW.2022 Antigens each heart were determined by an Olympus BX40 microscope with a micrometer (Olympus). 8236 MIMICRY AND AUTOANTIBODY CELL SIGNALING IN AUTOIMMUNE MYOCARDITIS of caspase 3, Formalin-fixed, paraffin-embedded

(18) Resistance to TGFβ suppression and improved anti-tumor responses in CD8⁺ T cells lacking PTPN22Nature communicationsJanuary 1, 0001Brownlie RJ, Garcia C, Ravasz M, Zehn D, Salmond RJ, Zamoyska R.

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ROCK2 Antibody

ROCK2 Antibody from Cell Signaling Technology

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Cell Signaling Technology

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ROCK2 Antibody from Cell Signaling Technology

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