Non-phospho-STEP (Ser221) (D74H3) XP ® Rabbit mAb 5659S from Cell Signaling Technology

Product Specs
ItemNon-phospho-STEP (Ser221) (D74H3) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $431.00 Inquire
Catalog Number5659S
Quantity100 µl
ApplicationsW, IP, IF-F
ReactivityH, M, R
TargetSTEP (Ser245) non-phosphate
ModificationsSTEP (Ser245) non-phosphate
HostRabbit
NCBI Gene AliasesPTPSTEP, STEP, STEP61
ClonalityMonoclonal
NCBI Full Gene Nameprotein tyrosine phosphatase non-receptor type 5
Research AreaNeuroscience
IsotypeIgG
CloneD74H3
Molecular Weight46, 61

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Mechanisms of mGluR‐dependent plasticity in hippocampal area CA2HippocampusJune 1, 2023Mahsa Samadi, Claire A. Hales, Daniel J. Lustberg, Shannon Farris, Madeleine R. Ross, Meilan Zhao, John R. Hepler, Nicholas H. Harbin, Emma S. J. Robinson, Paul J. Banks, et al.(1:500, Cell Signaling Technology, 4396), rabbit anti‐non‐phospho‐STEP (1:500, Cell Signaling Technology, 5659), mouse anti‐RGS14 (1:500, NeuroMab, 75‐170), and/or rabbit‐CaMKII alpha (1:500, Abcam, ab131468). Sections

(2) Moringa Oleifera Alleviates AÎ² Burden and Improves Synaptic Plasticity and Cognitive Impairments in APP/PS1 MiceNutrientsOctober 14, 2022Yacoubou Abdoul Razak Mahaman, Jun Feng, Fang Huang, Maibouge Tanko Mahamane Salissou, Jianzhi Wang, Rong Liu, Bin Zhang, Honglian Li, Feiqi Zhu, Xiaochuan Wang(23E5),pAb,Mouse,Cell Signaling Technology (4396) Anti-np-S221,np-STEP (S221),mAb,Rabbit,Cell Signaling Technology (5659) Anti-FYN,FYN,mAb,Mouse,ABclonal (A0086) Anti-p-Y416,p-Sar family Y416,pAb,Rabbit,ABclonal (RK06002) Anti-PP1CA,PP1CA

(3) Fbxo45-mediated NP-STEP(46) degradation via K6-linked ubiquitination sustains ERK activity in lung cancerMolecular oncologyAugust 1, 2022Wang Q, Xu C, Cai R, An W, Yuan H, Xu M.contamination. 2.2 Antibodies and reagents Antibodies against rabbit non‐phospho‐STEP (NP‐STEP; D74H3, #5659), HA‐tag (C29F4, #3724), p‐AKT (Ser473, 193H12, #4058), AKT (#9272), ERK (#4696), and pp38 (Thr180/Tyr182;

(4) RGS14 modulates locomotor behavior and ERK signaling induced by environmental novelty and cocaine within discrete limbic structuresPsychopharmacology (Berl)October 1, 2021Stephanie L. Foster, Daniel J. Lustberg, Nicholas H. Harbin, Sara N. Bramlett, John R. Hepler, David WeinshenkerP40101–0, Pel-Freez, Rogers, AR; 1:1000) or STEP (rabbit anti-Non-phospho-STEP, Cell Signaling Technology, #5659; 1:500) and RGS14 (mouse anti-RGS14, NeuroMab, Davis, CA, clone N133/21; 1:500). The sections were then

(5) A Bioactive Compound from Sanguisorba officinalis L. Inhibits Cell Proliferation and Induces Cell Death in 5-Fluorouracil-Sensitive/Resistant Colorectal Cancer CellsMolecules (Basel, Switzerland)June 24, 2021Zhang W, Peng C, Shen X, Yuan Y, Zhang W, Yang C, Yao M.Cell signaling and cancer: A mechanistic insight into drug resistance. Mol. Biol. Rep. 2019, 46, 5645–5659. [CrossRef] [PubMed] Ewen, M.E.; Lamb, J. The activities of cyclin D1 that drive tumorigenesis. Trends

(6) Ailanthone: A novel potential drug for treating human cancer (Review)Oncology LettersJune 9, 2020Haixiang Ding, Xiuchong Yu, Chen Hang, Kaijun Gao, Xifeng Lao, Yangtao Jia, Zhilong YanBiswal BK: Cell signaling and cancer: A mechanistic insight into drug resistance. Mol Biol Rep 46: 5645‑5659, 2019. 108. Koskela HL, Eldfors S, Ellonen P, van Adrichem AJ, Kuusanmäki H, Andersson EI, Lagström

(7) Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunityThe Journal of clinical investigationDecember 3, 2018Chen HM, van der Touw W, Wang YS, Kang K, Mai S, Zhang J, Alsina-Beauchamp D, Duty JA, Mungamuri SK, Zhang B, et al.antibody, and subsequently incubated with a secondjci.org Volume 128 Number 12 December 2018 5659 RESEARCH ARTICLE ary antibody conjugated to horseradish peroxidase. The antibodies for p-STAT1,

(8) Impaired Proteasomal Function in Human Osteoarthritic Chondrocytes Can Contribute to Decreased Levels of SOX9 and AggrecanArthritis & rheumatology (Hoboken, N.J.)July 1, 2018Serrano RL, Chen LY, Lotz MK, Liu-Bryan R, Terkeltaub R.protein clearance mechanisms in organismal ageing and age-related diseases. Review. Nat Commun. 2014; 5:5659. [PubMed: 25482515] 13. Lilienbaum A. Relationship between the proteasomal system and autophagy. Review.

(9) Combating autophagy is a strategy to increase cytotoxic effects of novel ALK inhibitor entrectinib in neuroblastoma cellsOncotargetFebruary 2, 2016Sanja Aveic, Marcella Pantile, Anke Seydel, Maria Rosaria Esposito, Carlo Zanon, Gary Li, Gian Paolo ToniniNB3, SH-SY5Y, and IMR32, kindly provided by Dr Luca Longo, from www.impactjournals.com/oncotarget 5659 Oncotarget RNA isolation, quantitative real-time polymerase chain reaction, and reverse-transcription polymerase chain reaction

(10) ZZ domain of dystrophin and utrophin: topology and mapping of a beta-dystroglycan interaction siteBiochemical JournalFebruary 1, 2007Karim Hnia, Dora Zouiten, Sonia Cantel, Delphine Chazalette, GÃ©rald Hugon, Jean-Alain Fehrentz, Ahmed Masmoudi, Ann Diment, Janice Bramham, Dominique Mornet, et al.Zinc coordination, function, and structure of zinc enzymes and other proteins. Biochemistry 29, 5647–5659 29 Ilsley, J. L., Sudol, M. and Winder, S. J. (2002) The WW domain: linking cell signalling to the membrane

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Non-phospho-STEP (Ser221) (D74H3) XP ® Rabbit mAb

Non-phospho-STEP (Ser221) (D74H3) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Non-phospho-STEP (Ser221) (D74H3) XP ® Rabbit mAb from Cell Signaling Technology

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