The CD79b Antibody (MMAE) from Biorbyt Monoclonal antibody to CD79b molecule. This antibody recognizes Homo Sapiens, and Human antigen. The CD79b Antibody (MMAE) has been shown to work in the following applications: EIA, Immunoassay, Cell Sorting, In Vivo, Isolation, ELISA, Flow Cytometry, Functional Assay, and Immunofluorescence.
Description
Anti-CD79b Reference Antibodyected antibody and Monomethyl auristatin E (MMAE) that can be used in combination with bendamustine and rituximab for the treatment of adult patients with at least two relapses or refractory diffuse large B-cell lymphoma. Polatuzumab vedotin binds to CD79b and is internalized by tumor cells. MMAE is cleaved from cells by lysosomal protease and promotes tumor cell apoptosis by inhibiting microtubule formation