Epcoritamab HY-P99931 from MedChemExpress | Biocompare.com

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Epcoritamab

Description

Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20⁺ tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines

Product Specs
ItemEpcoritamab
CompanyMedChemExpress
Price $650.00Supplier Page View Company Product Page
Catalog NumberHY-P99931
TypeChemical
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity1 mg
Purity99.84%
Research AreaCancer

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(1) Epcoritamab, a Novel, Subcutaneous CD3xCD20 Bispecific T-Cell-Engaging Antibody, in Relapsed or Refractory Large B-Cell Lymphoma: Dose Expansion in a Phase I/II TrialJournal of clinical oncology : official journal of the American Society of Clinical OncologyApril 20, 2023Thieblemont C, Phillips T, Ghesquieres H, Cheah CY, Clausen MR, Cunningham D, Do YR, Feldman T, Gasiorowski R, Jurczak W, et al.

(2) Epcoritamab induces potent anti-tumor activity against malignant B-cells from patients with DLBCL, FL and MCL, irrespective of prior CD20 monoclonal antibody treatmentBlood cancer journalFebruary 18, 2021van der Horst HJ, de Jonge AV, Hiemstra IH, Gelderloos AT, Berry DRAI, Hijmering NJ, van Essen HF, de Jong D, Chamuleau MED, Zweegman S, et al.

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