Crotedumab HY-P99357 from MedChemExpress | Biocompare.com

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Crotedumab

Description

Crotedumab (REGN1193) is a fully human IgG4 monoclonal antibody that binds and inhibits glucagon receptor (GCGR), with a K_D of 0.1 nM. Crotedumab can be used for the research of diabetes

Product Specs
ItemCrotedumab
CompanyMedChemExpress
Price $300.00Supplier Page View Company Product Page
Catalog NumberHY-P99357
TypeChemical
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity1 mg
Research AreaMetabolic Disease

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(1) A first-in-human pharmacodynamic and pharmacokinetic study of a fully human anti-glucagon receptor monoclonal antibody in normal healthy volunteersDiabetes, obesity & metabolismFebruary 1, 2018Kostic A, King TA, Yang F, Chan KC, Yancopoulos GD, Gromada J, Harp JB.

(2) Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and MonkeysEndocrinologyAugust 1, 2015Okamoto H, Kim J, Aglione J, Lee J, Cavino K, Na E, Rafique A, Kim JH, Harp J, Valenzuela DM, et al.

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