Ob-R (B-3) Alexa Fluor® 488 Antibody sc-8391 AF488 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemOb-R (B-3) Alexa Fluor® 488 Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $357.00Supplier Page View Company Product Page
Catalog Numbersc-8391 AF488
Antibody TypePrimary Antibody Conjugates
Clonalitymonoclonal
Reactivitymouse, rat, human
FormatPurified
ApplicationsWB(RGB), IF, IHC(P), FCM
CloneB-3
IsotypeIgG1
Hostmouse
Quantity200 µg/ml
Targetthe short form of Ob-R
NCBI Full Gene Nameleptin receptor
NCBI Gene AliasesLEPRD, CD295, Modb1, Leprb, Obr, LEP-R, db, obl, OB-RGRP, OB-R, LEPROT, obese-like, OBR, diabetes
Conjugate/TagAF488

Questions and Answers

Can this antibody be used for detecting the leptin receptor in human tissues?

Yes, the Ob-R (B-3) Alexa Fluor® 488 Antibody has been shown to work effectively for detecting the leptin receptor (Lepr) in human tissues, as it is reactive to Homo sapiens.

What applications is this antibody suitable for in my experiments?

This antibody is suitable for various applications, including Western Blotting (WB), Flow Cytometry (FCM), Immunofluorescence (IF), and Immunohistochemistry on paraffin-embedded sections (IHC-p).

Is this antibody effective for use in mouse models?

Yes, the Ob-R (B-3) Alexa Fluor® 488 Antibody is reactive to mouse tissues, making it suitable for studies involving mouse models.

How does the conjugation with Alexa Fluor® 488 enhance its utility in fluorescence-based applications?

The conjugation with Alexa Fluor® 488 allows for blue emission (≤499nm), which enhances the visibility and detection of the leptin receptor in fluorescence-based applications, facilitating clearer imaging and analysis in techniques such as Immunofluorescence and Flow Cytometry.

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

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(2) Treatment with bergamot (Citrus bergamia) leaves extract attenuates leptin resistance in obese ratsMolecular and cellular endocrinologyMay 1, 2023Nakandakare-Maia ET, Siqueira JS, Ferron AJT, Vieira TA, Palacio TLN, Grandini NA, Garcia JL, Belin MA, Altomare A, Baron G, et al.

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(4) Depletion of Zinc Causes Osteoblast Apoptosis with Elevation of Leptin Secretion and Phosphorylation of JAK2/STAT3NutrientsDecember 23, 2022Lee JK, Ha JH, Kim DK, Kwon J, Cho YE, Kwun IS.

(5) Endothelial PDGF-BB/PDGFR-β signaling promotes osteoarthritis by enhancing angiogenesis-dependent abnormal subchondral bone formationBone researchAugust 29, 2022Cui Z, Wu H, Xiao Y, Xu T, Jia J, Lin H, Lin R, Chen K, Lin Y, Li K, et al.

(6) Sox2 in the dermal papilla regulates hair follicle pigmentationCell reportsJuly 19, 2022Ng KJ, Lim J, Tan YN, Quek D, Lim Z, Pantelireis N, Clavel C.

(7) Hypothalamic regulation of energy homoeostasis when consuming diets of different energy concentrations: comparison between Tibetan and Small-tailed Han sheepThe British journal of nutritionApril 28, 2022Jing X, Guo Y, Degen A, Wang W, Kang J, Ding L, Shang Z, Long R, Zhou J.

(8) Greater Body Fatness Is Associated With Higher Protein Expression of LEPR in Breast Tumor Tissues: A Cross-Sectional Analysis in the Women's Circle of Health StudyFrontiers in endocrinologyJanuary 1, 2022Llanos AAM, Aremu JB, Cheng TD, Chen W, Chekmareva MA, Cespedes Feliciano EM, Qin B, Lin Y, Omene C, Khoury T, et al.

(9) Hydrogen sulphide attenuates neuronal apoptosis of substantia nigra by re-establishing autophagic flux via promoting leptin signalling in a 6-hydroxydopamine rat model of Parkinson's diseaseClinical and experimental pharmacology & physiologyJanuary 1, 2022Jiang W, Zou W, Hu M, Tian Q, Xiao F, Li M, Zhang P, Chen YJ, Jiang JM.

(10) A high-fat diet during pregnancy impairs memory acquisition and increases leptin receptor expression in the hippocampus of rat offspringNutritional neuroscienceJanuary 1, 2022Cortés-Álvarez NY, Vuelvas-Olmos CR, Pinto-González MF, Guzmán-Muñiz J, Gonzalez-Perez O, Moy-López NA.

(11) Leptin and inflammatory factors play a synergistic role in the regulation of reproduction in male mice through hypothalamic kisspeptin-mediated energy balanceReproductive biology and endocrinology : RB&EJanuary 20, 2021Chang B, Song C, Gao H, Ma T, Li T, Ma Q, Yao T, Wang M, Li J, Yi X, et al.

(12) The Ciji-Hua'ai-Baosheng II Formula Attenuates Chemotherapy-Induced Anorexia in Mice With H₂₂ Hepatocellular CarcinomaFrontiers in pharmacologyJanuary 1, 2021Xi S, Zhai X, Wang Y, Gong Y, Fu B, Gao C, Guo X, Li Y, Wang Z, Huang S, et al.

(13) Leptin: A Potential Link Between Obstructive Sleep Apnea and ObesityFrontiers in physiologyJanuary 1, 2021Ciriello J, Moreau JM, Caverson MM, Moranis R.

(14) AMPK mediates regulation of voltage-gated calcium channels by leptin in isolated neurons from arcuate nucleusAmerican journal of physiology. Endocrinology and metabolismDecember 1, 2020Bermeo K, Castro H, Arenas I, Garcia DE.

(15) Interstitial Leydig Cell Tumorigenesis-Leptin and Adiponectin Signaling in Relation to Aromatase Expression in the Human TestisInternational journal of molecular sciencesMay 21, 2020Duliban M, Gorowska-Wojtowicz E, Tworzydlo W, Rak A, Brzoskwinia M, Krakowska I, Wolski JK, Kotula-Balak M, Płachno BJ, Bilinska B.

(16) Role of TNFα and leptin signaling in colon cancer incidence and tumor growth under obese phenotypeBiochimica et biophysica acta. Molecular basis of diseaseMay 1, 2020Singh S, Mayengbam SS, Chouhan S, Deshmukh B, Ramteke P, Athavale D, Bhat MK.

(17) Leptin Resistance in the Ovary of Obese Mice is Associated with Profound Changes in the Transcriptome of Cumulus CellsCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyApril 30, 2020Wołodko K, Walewska E, Adamowski M, Castillo-Fernandez J, Kelsey G, Galvão A.

(18) Immunohistochemical analysis of adipokine and adipokine receptor expression in the breast tumor microenvironment: associations of lower leptin receptor expression with estrogen receptor-negative status and triple-negative subtypeBreast cancer research : BCRFebruary 11, 2020Llanos AAM, Lin Y, Chen W, Yao S, Norin J, Chekmareva MA, Omene C, Cong L, Omilian AR, Khoury T, et al.

(19) Novel Role of Lck in Leptin-Induced Inflammation and Implications for Renal AgingAging and diseaseDecember 1, 2019Kim DH, Park JW, Jeong HO, Lee B, Chung KW, Lee Y, Jung HJ, Hyun MK, Lee AK, Kim BM, et al.

(20) SUMO-specific protease 2 mediates leptin-induced fatty acid oxidation in skeletal muscleMetabolism: clinical and experimentalJune 1, 2019Koo YD, Lee JS, Lee SA, Quaresma PGF, Bhat R, Haynes WG, Park YJ, Kim YB, Chung SS, Park KS.

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Ob-R (B-3) Alexa Fluor® 488 Antibody

Ob-R (B-3) Alexa Fluor® 488 Antibody from Santa Cruz Biotechnology, Inc.

Questions and Answers

Santa Cruz Biotechnology, Inc.

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Ob-R (B-3) Alexa Fluor® 488 Antibody from Santa Cruz Biotechnology, Inc.

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