The SERPINE1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SERPINE1. This antibody recognizes Human, Mouse, and Rat antigen. The SERPINE1 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene