The TLE4 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TLE family member 4, transcriptional corepressor, and TLE4. This antibody recognizes Human, Mouse, and Rat antigen. The TLE4 Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity)