The [KO Validated] TNFAIP3 Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to carbonyl reductase 1, and CBR1. This antibody recognizes Human, and Mouse antigen. The [KO Validated] TNFAIP3 Rabbit pAb Antibody has been shown to work in the following applications: Western Blot.
Description
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene