The CLCN1 Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CLCN1. This antibody recognizes Human, and Mouse antigen. The CLCN1 Rabbit pAb Antibody has been shown to work in the following applications: Western Blot.
Description
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants