The Rabbit Anti-P53 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TP53, and tumor protein p53. This antibody recognizes Human antigen. The Rabbit Anti-P53 Antibody has been shown to work in the following applications: Other.
Description
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over