The Junctional Adhesion Molecule 1 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to F11R. This antibody recognizes Human antigen. The Junctional Adhesion Molecule 1 Rabbit mAb Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840)