The Rabbit Anti-ARRB1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ARRB1, and Arrestin beta 1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-ARRB1 Antibody has been shown to work in the following applications: Immunofluorescence, and Immunohistochemistry.
Description
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
This product can be used in analytical tools such as IHC, Immunofluorescence