The Methionine Aminopeptidase 2 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to METAP2, and methionyl aminopeptidase 2. This antibody recognizes Human, Mouse, and Rat antigen. The Methionine Aminopeptidase 2 Rabbit mAb Antibody has been shown to work in the following applications: Western Blot.
Description
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo