Rabbit Anti-PKCtheta Antibody from MyBioSource.com

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Rabbit Anti-PKCtheta Antibody

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MyBioSource.com's Rabbit Anti-PKCtheta Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Other. The Rabbit Anti-PKCtheta Antibody was generated using prkcq as the antigen and it reacts with Human.

Description

This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters