MyBioSource.com's TLR2 Mouse mAb is a Mouse monoclonal antibody. The TLR2 Mouse mAb Antibody was generated using TLR2, and toll like receptor 2 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Western Blot.
Description
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6