The [KO Validated] HERC4 Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to HERC4. This antibody recognizes Human, Mouse, and Rat antigen. The [KO Validated] HERC4 Rabbit pAb Antibody has been shown to work in the following applications: Western Blot.
Description
HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]