The [KO Validated] ECH1 Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ARL4A. This antibody recognizes Human, Mouse, and Rat antigen. The [KO Validated] ECH1 Rabbit pAb Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans, 4-trans-dienoyl-CoA, indicating that it is a delta3, 5-delta2, 4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators