MyBioSource.com's CYP4F2 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot. The CYP4F2 Polyclonal Antibody was generated using CYP4F2 as the antigen and it reacts with Human.
Description
Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B (4) omega-hydroxylase by mediating conversion of leukotriene-B (4)(LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene- B (4)(20-OH LTB4)(PubMed:9799565)