The Rabbit Anti-SphK2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to sphingosine kinase 2, and SPHK2. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-SphK2 Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
sphingosine kinase 2 (SPHK2), Homo sapiens. This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]