The [KO Validated] OCRL Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to OCRL, and OCRL inositol polyphosphate-5-phosphatase. This antibody recognizes Human, Mouse, and Rat antigen. The [KO Validated] OCRL Rabbit pAb Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants