The Rabbit Anti-IL-4Ralpha Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to IL4R, and Interleukin 4 Receptor. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-IL-4Ralpha Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2