The LIN28 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Lin-28 Homolog A, and LIN28A. This antibody recognizes Human, and Mouse antigen. The LIN28 Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues