The Rabbit Anti-AGT Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to AGT, and Angiotensinogen. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-AGT Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
This product can be used in analytical tools such as Western Blot, IHC