MyBioSource.com's Anti-CD3e [898H2-6-15], Rabbit IgG is a Rabbit monoclonal antibody. The Anti-CD3e [898H2-6-15], Rabbit IgG Antibody was generated using CD3E, and CD3e molecule as the antigen. It reacts with Porcine. This antibody has been shown to work in applications such as: Flow Cytometry, and Immunohistochemistry.
Description
The initial identification of 898H2-6-15 showed that it recognised the T-cell receptor-associated glycoprotein CD3, in particular the e chain (Huang et al, 1999). More recently, the 898H2-6-15 VH and VL domains were reformatted into a scFv and conjugated to diphtheria toxin (Wang et al, 2011). This version of the antibody as an 'immunotoxin' has been shown to deplete circulating T cells in swine without observation of any clinical toxicities