The BMP2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to BMP2, and Bone Morphogenetic Protein 2. This antibody recognizes Human, Mouse, and Rat antigen. The BMP2 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients