The Rabbit Anti-Cleaved-Caspase-2 p18 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CASP2, and Caspase 2. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Cleaved-Caspase-2 p18 Antibody has been shown to work in the following applications: Western Blot.
Description
Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival (PubMed:15073321). Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress (PubMed:15073321)