MyBioSource.com's Rabbit Anti-MDM4 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Other. The Rabbit Anti-MDM4 Antibody was generated using MDM4, and MDM4 regulator of p53 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions