The [KO Validated] CD146/MCAM Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to XCR1. This antibody recognizes Human, and Mouse antigen. The [KO Validated] CD146/MCAM Rabbit pAb Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration